Carmichael & Nuttall, 2005). Furthermore, there are three types of IgNAR, type 1, type 2, and type 3 (Streltsov, Carmichael & Nuttall, 2005). Figure 1 (Wikipedia) Having 5 five constant domains (CH) per chain instead of three, containing several disulfide bonds in unusual positions, and forming an extension of CDR3 loop cause IgNAR to be more stable than conventional antibodies. Figure 2 (Dooley, Helen) Besides, in common antibodies, Fab (50 kDa) that contains VH and VL chains…
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