Headache Currents CURRENT LITERATURE: BASIC SCIENCE The Hypothalamus, Pain, and Primary Headaches he hypothalamus integrates a multitude of functions including endocrine and autonomic control, thermoregulation, sleep, appetite, emotional behavior and arousal, and governs the rhythmicity and timing of many body functions. Evidence is emerging from neuroimaging studies in man and animal experimental studies that the hypothalamus plays a crucial role in nociceptive processing, particularly…
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