an imprint of Elsevier Inc. 7 Schizophrenia (Cont.) Clinical Manifestations Negative symptoms Reflect a decrease, deficit, or loss of normal functions Considered to be restricted affect; avolition and asociality Associated with dopamine D1 receptor activity Manifestations include social withdrawal and isolation, dull or blunted emotional affect, poverty of speech, posturing, and autism Copyright © 2013, 2010, 2005 by Saunders, an imprint of Elsevier Inc. 8…
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