The Integumentary System The Three Main Layers of Skin: 1. Epidermis: The first layer of skin is called the Epidermis. It is composed of stratified squamous epithelium that is keratinized. It contains the keratinocytes and melanocytes, it is avascular, and is the tissue layer above skin. It is the BARRIER Layer. The Epidermis is made up of five different layers: Stratum Corneum: known as the “horny” layer, dead, stratified squamous, and it looks rough. This layer can become thick (callus) from…
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