Lecture 15 – Antibody Effector Mechanisms Antibodies -Abs exist to protect us from extra and intracellular bacteria and parasites, extracellular fungi, viruses, and parasitic worms Effector Function of Abs -neutralization -opsonization -complement activation -antibody dependant cell cytotoxicity or ADCC (cell killing) -mast cell activation Ab Structure -the N-terminus end of the Ab polypeptide is the variable region, which is ‘variable’ as a result of VDJ recombination -the C-terminus…
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