given year, 5% of US adults have clinically significant depression Lifetime prevalence: 10% Various duration and triggers MDD: Genes & The Environment Moderate degree of heritability Linked to ↑ anxiety disorders, ADD, substance abuse, OCD, bulimia, migraines, IBS, and other syndromes among relatives Relatives of women with early-onset depression have ↑ risk MDD: Gene + Environment Interaction 5-HTT (Serotonin Transporter) Short-short, short-long, long-long Short form: reduced…
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