Lactate and Choline Metabolites Detected In Vitro by Nuclear Magnetic Resonance Spectroscopy Are Potential Metabolic Biomarkers for PI3K Inhibition in Pediatric Glioblastoma Nada M. S. Al-Saffar1*, Lynley V. Marshall2,3,4, L. Elizabeth Jackson1, Geetha Balarajah1¤, Thomas R. Eykyn1,5, Alice Agliano1, Paul A. Clarke3,6, Chris Jones2,3, Paul Workman3,6, Andrew D. J. Pearson3,4, Martin O. Leach1 1 Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute…
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