Diabetes and obesity together also place an enormous economic burden on our society. The direct and indirect annual costs of obesity in the United States are $113 billion and $174 billion for diabetes, cumulatively $3 trillion over the past decade [5]. The problem is also expanding globally. In China, 92 million individuals have diabetes, 60% of whom are undiagnosed. Another 148 million have metabolic syndrome, 100% of whom are undiagnosed [6]. Overweight and obesity are, for the majority, markers…
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