epithelial barriers. Spread- Agent spreads from site of entry. Lateral propagation- from site of entry to contiguous tissue. Dissemination- to distant sites Multiplication- Agent multiplies. Affected by incubation, time, pH, temperature, & osmotic pressure Damage-The agent, host response, or both cause tissue damage Outcome-Agent wins out, host wins out, or they coexist Big Four Gram - cocci Gram + rods Moraxella Bacillus Neisseria Clostridium Veillonella Listeria Gram - rods Gram + cocci Pseudomonas…
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