Mastitis also called mammitis is an inflammatory reaction of udder tissue to bacterial, chemical, thermal or mechanical injury. It is a global issue, which is a serious threat to animal health, also reduces the quantity and quality of milk (Patnaik et al., 2013) and is responsible for more than $2 billion annual losses to the US dairy industry (Sordillo LM, Streicher KL, 2002). It is regarded as a serious disease that causes reduced milk quality and animal welfare, extensive losses due to production loss, increased treatment costs and labor, and higher culling rates (Halasa et al., 2007). The udder is one of the most important physiological and conformational characteristics of the cow due to its importance for milk production.
Consequently,