History and Ethics of Genetic Engineering By: The Late Dr. T.D. Singh on March 21, 2009, 7:40 a.m. Click to see larger image In 1966, B. Weiss and C.C. Richardson isolated DNA ligase, an enzyme that could be used to “ligate” or paste together two strands of DNA. Thus, researchers could now attach two or more DNA molecules or break it into fragments. In 1972, Paul Berg used restriction enzyme to cut DNA, and then a ligase to paste two DNA strands together to form a hybrid circular molecule…
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