DNA Task 1

DNA Task 1
Stacii Lightfoot
000449887
May 2, 2015

DNA Task 1

(Wolfe,2000.) In DNA the helicase enzyme causes the double strand DNA to split apart forming a replication bubble. Single strand binding protein pulls and keeps the DNA strands apart. DNA polymerase III reads the DNA strand from 3’ to 5’ direction, but synthesizes in the 5’­3’ direction. RNA primer is a strand of about 10 RNA nucleotides that is required for DNA replication. Primase is an enzyme that synthesizes RNA primer. There is continuous growth in the leading strand DNA while the lagging strand growth is fragmented. Okazaki fragments are found in between the DNA segments of the lagging strand.(Wolfe,2000).

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(Wolfe, 2000).

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(Thompson, 2014).

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(Thinkwell animation,2014).

DNA Task 1

(Thinkwell Animation,2014).

DNA Task 1

(Thinkwell animation,2014).

DNA Task 1

(Thinkwell animation,2014).

DNA Task 1

(Thinkwell animation,2014).

DNA Task 1

(Wang, Philpot, 2005).

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(IB Biology,2007).

The Death cap mushroom ,
Amanita phalloides, produces fatal cellular toxins called
Amanitins. (Santi, 2012).The death cap mushrooms toxins are not destroyed by cold storage or cooking.After ingestion of the mushroom the toxins are absorbed in the gastrointestinal tract.
From there they cross to the liver and eventually the kidney.Death usually occurs 6­16 days post ingestion.(Wikipedia,2015). Amanitins are hepatorenal toxic. These toxins cause acute liver failure and acute tubular necrosis in the kidneys.(Santi, 2012).
Amanitins works by inhibiting
RNA polymerase II thus stopping protein synthesis and cell metabolism. (Wikipedia,2015). By inhibition the enzyme RNA polymerase II the process of transcription (making new mRNA) and translation (using mRNA to make proteins) can not be performed leading to cellular necrosis
.
(
Hudon­Miller, S. (2012).

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(Hudson­Miller, 2012).

DNA Task 1

(Hudson­Miller,2012).

DNA Task 1

References
Amanita phalloides. (2015).
Wikipedia. Online. Retrieved from http://en.wikipedia.org/wiki/Amanita_phalloides Hudon­Miller, S. (2012) Death cap mushrooms.
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