temp, heart failure, asthma. Abnormal skin color: -Jaundice: liver fails to excrete bile, accumulates in skin, yellow. -Addison’s Disease: pituitary secretes excess adrenocorticotropic hormone, stimulates melanocytes, excess melanin, bronzing. -Albinism: genetic mutation in melanin biosynthesis pathway, lack pigmentation in skin, hair and eyes. -Vitiligo: autoimmune disease ! destruction of melanocytes. Vitamin D3 Production:Cells of stratum spinosum and basale. UV energy + cholesterol = Vitamin D3…
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