Depression

it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble doing normal day­to­day activities, and depression may make you feel as if life isn't worth living. http://www.mayoclinic.org/diseases­conditions/depression/basics/definition/con­20032977

What is depression? What causes depression? 87
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Depression, also known as major depression, clinical depression or major depressive disorder is a medical illness that causes a constant feeling of sadness and lack of interest. Depression affects how the person feels, behaves and thinks. Depression can lead to emotional and physical problems. Typically, people with depression find it hard to go about their day­to­day activities, and may also feel that life is not worth living.

http://www.medicalnewstoday.com/articles/8933.php

picture of depr 1 http://www.huffingtonpost.com/2014/09/24/depression­symptoms_n_5868190.html http://www.healthline.com/health/depression/statistics­infographic

“If chronic inflammatory changes are a common feature of depression, that could predispose depressed patients to neurodegenerative changes in later life,” according to a 2007 article in Neurochemical Research
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“M.C.I. is an independent risk factor for Alzheimer’s disease, and people with M.C.I. often have depression and anxiety,” said Dr.
David Loewenstein, a professor of psychology and behavioral sciences at the University of Miami Miller School of Medicine. “The depression reported could have been a co-morbid condition of underlying early stage disease.”

Deborah Barnes, associate professor of psychiatry, epidemiology and biostatics at the University of California, San Francisco.
She is the author of a study of 13,535 members of Kaiser
Permanente, a California-based health maintenance organization, published a year ago in JAMA Psychiatry that found that older adults were three times more likely to develop vascular dementia if they’d suffered from depression starting in middle age and continuing on in later life.
Dr. Barnes also wrote a 2011 paper in The Lancet that estimated that almost 15 percent of Alzheimer’s disease cases in the United
States are “potentially attributable to depression”