Adaptation, Infection and sterilization, Carcinogenesis, Hypersensitivity and systemic effects, Long term stability, and Fatigue tests. 3.1 Blood vessels: The development of peripheral vascular reconstructive surgery has been closely associated with the development of prosthetic vascular grafts. The quest for an ideal vascular conduit began soon after Carrel and Guthrie demonstrated in a canine model that homologous and heterologous artery and vein segments could be used as arterial substitutes. Although…
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